Bi-Est (Estriol/Estradiol) Cream & Progesterone Capsules to

Relieve Symptoms

Feel Your Best

Find Balance

● In Stock

For Her

Menopause Relief

A custom-compounded Bi-Estrogen cream that blends estradiol and estriol to restore hormonal balance and relieve common menopause symptoms. Paired with required Progesterone capsules to support deeper sleep, steadier mood, and balanced estrogen levels.

Personalized, balanced hormone therapy for menopause relief.
Simple topical cream for effortless daily application.
Addresses hot flashes, night sweats, vaginal dryness, and more.

From $102 per month

Billed as $305 every 3 months

● In Stock

✔ Free Online Visit (Saving $40)

✔ Free Online Prescription (Saving $20)

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5.0

Great Customer Service

🇺🇸 Prepared in a U.S. licensed pharmacy

✓ Prescription Included

THE POWER OF BIOIDENTICAL HORMONES

A More Natural Path to Hormonal Balance

Bioidentical hormones are identical to those your body produces, providing a clear advantage. By supplementing naturally declining hormone levels, you have the best opportunity to feel your best again.

Identical to hormones your body naturally produces

Helps restore hormones to optimal levels as you age

Aims to limit negative side effects

A natural and effective option for feeling your best

Tailored therapy to support your body's needs

EFFORTLESS & CONVENIENT

Complete Balance for Real Results

When estrogen is prescribed, Progesterone isn’t optional — it’s essential. Together, they bring your hormones back into harmony so you can feel like yourself again. This combination therapy supports what matters most in your daily life:

Restful, uninterrupted sleep — no more tossing and turning.

Steady mood and mental clarity — fewer ups and downs, more focus.

Natural protection for bone and breast health — restoring balance from the inside out.

Easy, topical application — smooth cream that absorbs quickly without residue.

Precision dosing — one pump delivers the exact amount your provider recommends.

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Targeted Relief for Menopause Symptoms

Our Bi-Est Cream is designed to provide full-spectrum support for your unique journey.

Relieve Hot Flashes & Night Sweats

Our dual-estrogen formula effectively tackles common menopausal symptoms, helping you feel more comfortable day and night.

Improve Vaginal & Urinary Health

Estriol excels at easing dryness, discomfort, and other vaginal and urinary symptoms associated with menopause.

Balanced, Bioidentical Hormones

We use hormones identical to those your body produces, offering a natural approach to find your balance and feel your best again.

Support for Mood & Cognition

Estradiol is a potent estrogen that helps with menopausal symptoms like mood swings and cognitive changes.

Feel Like Yourself Again

When your hormones shift, it can affect everything—your energy, sleep, mood, and even how connected you feel in your relationships. HRT is here to help bring your body back into balance, so you can feel more at home in yourself.

Care That Fits Into Your Life

This isn’t one-size-fits-all. Your treatment is tailored around you—your goals, your comfort, your pace. And it’s private, simple, and supported by providers who actually listen.

More Than Medicine, It’s Confidence

HRT isn’t just about numbers or prescriptions. It’s about waking up with energy, finding joy in the little things, and feeling present again—in your work, your relationships, and your own skin.

Safe, Simple, and Personalized Care.

Your wellness journey is unique. Our Bi-Est cream provides a simple, non-invasive way to manage menopausal symptoms under the guidance of a licensed provider and our expert pharmacy team.

Topical Cream

Custom Compounded

Dual-Estrogen Formula

Bioidentical Hormones

Quality Tested

Prescription Included

Your Path to Balanced Hormones in 4 Simple Steps

Complete a brief medical intake form online.

Consult with a licensed provider for your personalized plan.

Receive your custom-compounded cream by mail.

Access ongoing care and pharmacist support.

Choose the plan that's right for you. No hidden fees.

Bi-Est Cream & Progesterone Capsules
(90-Day Supply)

Feel your best for the price of a coffee — under $3.50 a day, billed as $305 every 3 months.

3-Month Plan

Shipped every 3 months.

$102 per month

Billed as $305 every 3 months

Start Free Online Visit

Your HRT Questions, Answered

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MintRx connects patients with licensed providers who may prescribe medication through state-licensed pharmacies. Prescription medication only available if prescribed after an online consultation with a healthcare provider. Compounded medications are meant to be prepared as individualized to the patient and are not reviewed or approved by the FDA.

Plans are offered as a subscription service which you can cancel at any time. Actual product packaging may appear differently than shown.

A Treatment Plan Fine-Tuned To You

Our compounded Bi-Est cream offers a bioidentical, natural source option that is made specifically for each individual patient.

Estrogen & Progesterone Benefits

Combines estradiol (E2) and estriol (E3) to address a wide range of menopausal symptoms, with progesterone supporting hormonal balance.

Custom Compounded

Unlike mass-produced HRT, our cream is customized with multiple concentration options for a personalized plan.

Bioidentical Hormones

Uses hormones identical to those your body makes, offering a natural and effective approach to hormone balance.

Professional Oversight

Requires a prescription and medical consultation, with ongoing support from licensed pharmacists to ensure your success.